Otay Mesa Trip

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence
    • payments icon
    Better together
    Save up to ₹43,962 when you book a flight and hotel together*
    lob hotels icon
    Find the right fit
    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon
    Rest easy
    Plan, book, and manage your trip all in one place
Beautiful view of the beach with palm trees

Black Friday: Members save 30%+

Members save 30%+ on selected hotels until December 4 with our Black Friday deals. Stay by December 15, 2025.
Unlock Black Friday deals

Where to stay in Otay Mesa

Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Otay Mesa
Default Image

Downtown San Diego

2 out of top 10 points of interest in this area
4.5/5(138 area reviews)

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Balboa Park are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Find hotel + flight trips in Downtown San Diego

Find the Best Otay Mesa Vacation Packages

Otay Mesa Hotel Deals

Wyndham Garden San Diego Near SeaWorld
Wyndham Garden San Diego Near SeaWorld
3 out of 5
3737 Sports Arena Blvd, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is ₹8,361 per night from 24 Nov to 25 Nov
₹8,361
₹9,422 total
includes taxes & fees
24 Nov - 25 Nov
7.2/10 Good! (3,548 reviews)
"Good value for your money"

Reviewed on 23 Nov 2024

Wyndham Garden San Diego Near SeaWorld
Manchester Grand Hyatt San Diego
Manchester Grand Hyatt San Diego
4 out of 5
1 Market Pl, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is ₹12,846 per night from 18 Dec to 19 Dec
₹12,846
₹18,497 total
includes taxes & fees
18 Dec - 19 Dec
8.8/10 Excellent! (2,864 reviews)
"Close to the conference centre and restaurants"

Reviewed on 22 Nov 2024

Manchester Grand Hyatt San Diego
Wyndham San Diego Bayside
Wyndham San Diego Bayside
4 out of 5
1355 N Harbor Drive, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is ₹12,850 per night from 16 Dec to 17 Dec
₹12,850
₹14,481 total
includes taxes & fees
16 Dec - 17 Dec
8.2/10 Very Good! (5,530 reviews)
"I booked the room with a bay view. The view is beautiful, and the sunset is gorgeous. However, the drawbacks are that the room is old and noisy because it is next to the elevator. The bathroom sink has a poor design that makes it difficult to wash my hands. The walkable area is nice because it is ..."

Reviewed on 23 Nov 2024

Wyndham San Diego Bayside
See all 4,427 properties in Otay Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an Otay Mesa holiday package cost?
Starting from as low as , a holiday package is your ticket to cheaper travel. Create your own Otay Mesa escape by choosing from our wide range of hotels, airfares and rental cars.
How do I get a cheap travel package to Otay Mesa?
Our Otay Mesa holiday packages mean plenty of savings for the savvy wanderer. For the best deal, simply bundle your hotel, flights and extras (such as activities) into a neat and tidy package. But impressive bargains are only the start of your next amazing adventure. When you book with Expedia, you’ll have more than 550 air carriers and 1,000,000 hotel options all over the world to pick from. No matter your budget or style, there’s a package that’s perfect for you.
Where should I stay in Otay Mesa?
A getaway to Otay Mesa wouldn’t be complete without paying a visit to North Island Credit Union Amphitheatre, Aquatica and White Water Canyon. Spend your evenings close to these tourist attractions and make sightseeing simple.
What are the top hotels in Otay Mesa?
Book a stay at Holiday Inn Express Hotel & Suites San Diego Otay Mesa, an IHG Hotel. It’s one of this neighbourhood’s most sought-after hotels. Another reputable option in Otay Mesa is Quality Suites San Diego Otay Mesa.
How far in advance should I book my Otay Mesa holiday?
Your best bet is to book early. Air carriers typically release flights around a year prior to departure, and this is an ideal opportunity to score some rock-bottom prices. Boss just told you to take your holiday time next month? That’s alright! Expedia are never short on fantastic deals to send you on the getaway of your dreams, at a price you can afford.
What does an Expedia Otay Mesa travel package include?
It comes down to what you want. If you’re travelling alone, you might decide to bundle flights and hotels. Bringing the entire family to Otay Mesa? A travel package that includes rental cars, flights and hotels might be a better fit. Expedia gives you the flexibility and freedom to tailor-make your travel package.
What should I know before booking an Otay Mesa travel package?
When you book your flights, hotels and car rentals together, you’ll land terrific discounts. Whether you’re organising an island getaway in a villa or prefer to stay in a cosy apartment in the city, Expedia can help make it happen.
Can I choose my airline with an Otay Mesa Expedia holiday package?
You can, and with over 550 airlines to select from worldwide, you have loads of choice. Look through the available options and find out which airline best suits your needs and budget.
If I'm not able to travel, can I cancel my Otay Mesa holiday package?
Don’t worry if you’re rethinking your Otay Mesa holiday package — it’s possible to change or amend your booking. And if you’ve booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your hotel, airline or car rental company. We get that life can sometimes throw a spanner in the works, so make your way to our Customer Service Portal if that happens. When you’re ready to make changes, we’re ready to help.

Discover the most popular places to visit in Otay Mesa

San Diego Zoo featuring zoo animals, landscape views and a pond

San Diego Zoo

4.5/5(47 reviews)

One of the largest zoos in America housing around 4000 creatures, San Diego Zoo offers an enchanting and educational experience for visitors of all ages.

San Diego Zoo
Mission Bay featuring a beach

Mission Bay

4.5/5(31 reviews)

Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.

Mission Bay
Petco Park

Petco Park

4.5/5(17 reviews)

Purchase a hot dog and watch the San Diego Padres, California’s southernmost Major League Baseball team, play on their home field.

Petco Park
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.