All hotels in Southeast Missouri, Missouri
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
All hotels in Southeast Missouri, Missouri
We have found 530 Southeast Missouri, Missouri hotels
- Baymont Inn and Suites by Wyndham Farmington, MO
- La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
- Pear Tree Inn Cape Girardeau Near the Medical Center
- Pear Tree Inn Sikeston
- Days Inn and Suites by Wyndham Sikeston
- Holiday Inn Express & Suites Perryville, an IHG Hotel
- Drury Inn & Suites Poplar Bluff
- Fairfield Inn & Suites by Marriott Poplar Bluff
- Comfort Suites Jackson-Cape Girardeau
- Hampton Inn Poplar Bluff
- Drury Inn & Suites Hayti Caruthersville
- Comfort Inn Festus - St Louis South
- New Orleans Inn Portageville
- Super 8 by Wyndham Perryville
- Comfort Inn Poplar Bluff North
- Drury Inn & Suites Jackson MO
- Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel
- Quality Inn Farmington
- Super 8 by Wyndham Poplar Bluff Missouri
- Super 8 by Wyndham Farmington
- Microtel Inn & Suites by Wyndham Sainte Genevieve
- Super 8 by Wyndham Bonne Terre
- Bullwinkles Rustic Lodge
- Holiday Inn Express & Suites Farmington, an IHG Hotel
- Super 8 by Wyndham Charleston/Sikeston East MO
- Current River Inn
- Crown Pointe Lodge, BW Signature Collection
- Quality Inn Hayti North
- Shepherd Mountain Inn
- Econo Lodge Dexter
- Travelodge by Wyndham Dexter
- Days Inn by Wyndham Perryville
- Econo Lodge
- Quality Inn
- Red Roof Inn Marston
- Wilderness Lodge
- Rosener's Inn and banquet center
- Super 8 by Wyndham Pevely
Let Expedia take you to the best Hotels in Southeast Missouri. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.